Unamee

Description

Cordyceps - Functionality of the first respiratory tract. Natural defenses of the body. Tonic action and metabolic support.

Scutellaria - Natural defenses of the body. Digestive and hepatic function. Articular functionality.

Deeply rooted in the tradition of natural medicine, without ever losing sight of science, CORDYCEPS-CURCUMA-SCUTELLARIA enhance a new synergy created and encapsulated in the unique formula of UNAME. The three principles enshrined in each capsule of UNAME represent some of the pillars of Kampo medicine from Traditional Chinese Madeicine and Ayurvedic Medicine.

In the tradition of HOPISPHARMA, we have ensured that by enclosing together such herbal principles from these three fundamental schools of medicine we obtain a formula that is always balanced in structure and effects while still maintaining high dosages and in full harmony with each other.

References and directions to TCM are in no way intended to be a substitute for Western medicine, medical advice and a varied diet.

INGREDIENTS

- CORDYCEPS SINENSIS (SYN. PAECILOMYCES HEPIALI CHEN) MYCELIUM E.S. tit. 30 % polysaccharides*

- SCUTELLARIA BAICALENSIS GIORGI RADIX E.S. tit. 98 % balicalein*

- TURMERIC LONGA L. RHIZOME E.S.*/**

HOW TO USE THE PRODUCT

1 capsule daily on a full stomach.

DAILY DOSES

Cordyceps sinensis Tit 30% in polysaccharides 250mg

Scutellaria baicalensis Tit 98% in baicalein 175mg

Curcuma longa ** 72mg

FORMAT

60 cps. of 500mg

* country of origin R.P.China

** according to the Commission Implementing Regulation (EU) 2018/456 and No. 2880 30/01/23 only non-titrated dry extract.

Turmeric carries the following ministerial warning "IMPORTANT WARNING In case of impaired liver function, biliary function, or gallstones, use of the product is not recommended.
Do not use during pregnancy and lactation. Do not use for prolonged periods
Without consulting your doctor. If you are taking medication, you should seek the advice of your doctor."

BIBLIOGRAPHY

Burnett, Bruce & Jia, Qi & Zhao, Y & Levy, Robert. (2007). A Medicinal Extract of Scutellaria baicalensis and Acacia catechu Acts as a Dual Inhibitor of Cyclooxygenase and 5-Lipoxygenase to Reduce Inflammation. Journal of medicinal food. 10. 442-51. 10.1089/jmf.2006.255.

 Moghe G, Last RL (2015) Something old, something new: conserved enzymes and the evolution of novelty in plant specialized metabolism. Plant Physiol 169:1512-1523

-De Carvalho, R.S.M.; Duarte, F.S.; De Lima, T.C.M. Involvement of GABAergic non-benzodiazepine sites in the anxiolytic-like and sedative effects of the flavonoid baicalein in mice. Behav. Brain. Res., 2011, 221, 75-82. CrossRef DOI: http://dx.doi.org/10.1016/j.bbr.2011.02.038

-Wang Y. H., Yu H. T., Pu X. P. & Du G. H. Baicalein prevents 6-hydroxydopamine-induced mitochondrial dysfunction in SH-SY5Y cells via inhibition of mitochondrial oxidation and up-regulation of DJ-1 protein expression. Molecules 18, 14726-14738 (2013). 

-Liu A. et al. Baicalein protects against polymicrobial sepsis-induced liver injury via inhibition of inflammation and apoptosis in mice. Eur. J. Pharmacol. 748, 45-53 (2015).

-Mabalirajan U. et al. Baicalein reduces airway injury in allergen and IL-13 induced airway inflammation. PLoS One 8, e62916 (2013).

-Guo Z. et al. Baicalein inhibits prostate cancer cell growth and metastasis via the caveolin-1/AKT/mTOR pathway. Mol. Cell. Biochem. 406, 111-119 (2015).

-Georas S. N. & Rezaee F. Epithelial barrier function: At the frontline of asthma immunology and allergic airway inflammation. J. Allergy Clin. Immunol. 134, 509-520 (2014).

-Mabalirajan U. et al. Baicalein reduces airway injury in allergen and IL-13 induced airway inflammation. PLoS One 8, e62916 (2013).

-Lee J. Y., Kim J. M. & Kim C. J. Flavones derived from nature attenuate the immediate and late-phase asthmatic responses to aerosolized-ovalbumin exposure in conscious guinea pigs. Inflamm. Res. 63, 53-60 (2014).

-Yun M. Y. et al. Therapeutic effects of Baicalein on atopic dermatitis-like skin lesions of NC/Nga mice induced by dermatophagoides pteronyssinus. Int. Immunopharmacol. 10, 1142-1148 (2010).

-Kimata M., Inagaki N. & Nagai H. Effects of luteolin and other flavonoids on IgE-mediated allergic reactions. Planta Med. 66, 25-29 (2000).

- Kimata M, Shichijo M, Miura T, Serizawa I, Inagaki N, Nagai H. Effects of luteolin, quercetin and baicalein on immunoglobulin E-mediated mediator release from human cultured mast cells. Clin. Exp. Allergy 2000;30:501- 508.

-Dubravko Jelić, Agnieszka D. Lower-Nedza, Adelheid H. Brantner, et al, "Baicalin and Baicalein Inhibit Src Tyrosine Kinase and Production of IL-6," Journal of Chemistry, vol. 2016, Article ID 2510621, 6 pages, 2016. doi:10.1155/2016/2510621

-B. Q. Li, T. Fu, W.-H. Gong et al, "The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines," Immunopharmacology, vol. 49, no. 3, pp. 295-306, 2000.

-T. Nagai, R. Moriguchi, Y. Suzuki, T. Tomimori, and H. Yamada, "Mode of action of the anti-influenza virus activity of plant flavonoid, 5,7,4′-trihydroxy-8-methoxyflavone, from the roots of Scutellaria baicalensis," Antiviral Research, vol. 26, no. 1, pp. 11-25, 1995.

-R. H. Fitts, "Cellular mechanisms of muscle fatigue," Physiological Reviews, vol. 74, no. 1, pp. 49-94, 1994.

-J. Song,Y.Wang, M. Teng et al, "Studies on the antifatigue activities of Cordyceps militaris fruit body extract in mouse model," Evidence-based Complementary and Alternative Medicine, vol. 2015, Article ID 174616, 2015.

 -T. Li andW. Li, "Impact of polysaccharides from Cordyceps on anti-fatigue in mice," Scientific Research and Essays, vol. 4, no. 7, pp. 705-709, 2009.

-J.-Y. Wu, H.-P. Leung, W.-Q. Wang, and C.-P. Xu, "Mycelial fermentation characteristics and anti-fatigue activities of a Chinese caterpillar fungus, ophiocordyceps sinensis strain Cs-HK1 (Ascomycetes)," International Journal of Medicinal Mushrooms, vol. 16, no. 2, pp. 105-114, 2014. -R.Kumar, P. S. Negi, B. Singh, G. Ilavazhagan, K. Bhargava, and N. K. Sethy, "Cordyceps sinensis promotes exercise endurance capacity of rats by activating skeletal muscle metabolic regulators," Journal of Ethnopharmacology, vol. 136, no. 1, pp. 260-266,

2011. -C.-H. Dong and Y.-J. Yao, "In vitro evaluation of antioxidant activities of aqueous extracts fromnatural and culturedmycelia of Cordyceps sinensis," LWT - Food Science and Technology, vol. 41, no. 4, pp. 669-677, 2008.

-M. G. Feng, Q. G. Zhou, and G. H. Feng, "Vasodilating effect of cultured Cordyceps sinensis (Berk) Sacc. mycelia in anesthetized dogs," Zhong Yao Tong Bao, vol. 12, no. 12, pp. 41-60, 1987. -T. Jia and B. H. S. Lau, "The immune-enhancing effect of Chinese herbal medicine Cordyceps sinensis on macrophage

J774," Zhongguo Yao Xue Za Zhi (Zhongguo Yao Xue Hui: 1989), vol. 32, no. 3, pp. 142-144, 1997.

-B.-M. Huang, C.-C. Hsu, S.-J. Tsai, C.-C. Sheu, and S.-F. Leu, "Effects of Cordyceps sinensis on testosterone production in normal mouse Leydig cells," Life Sciences, vol. 69, no. 22, pp. 2593-2602, 2001.

-S. P. Li, G. H. Zhang, Q. Zeng et al, "Hypoglycemic activity of polysaccharide, with antioxidation, isolated from cultured Cordyceps mycelia," Phytomedicine, vol. 13, no. 6, pp. 428-433, 2006.

-Jin Li, Liping Zhong, Haibo Zhu, and Fengzhong Wang, "The Protective Effect of Cordycepin on D-Galactosamine/Lipopolysaccharide-Induced Acute Liver Injury," Mediators of Inflammation, vol. 2017, Article ID 3946706, 12 pages, 2017. doi:10.1155/2017/3946706

-Tianyi He, Ruxing Zhao, Yiran Lu, et al, "Dual-Directional Immunomodulatory Effects of Corbrin Capsule on Autoimmune Thyroid Diseases," Evidence-Based Complementary and Alternative Medicine, vol. 2016, Article ID 1360386, 9 pages, 2016. doi:10.1155/2016/1360386

-C.-Q. Ling, X.-Q. Yue, and C. Ling, "Three advantages of using traditional Chinese medicine to prevent and treat tumor," Journal of Integrative Medicine, vol. 12, no. 4, pp. 331-335, 2014.

-B. Ji, J. Ye, C.-L. Li, Y.-H. Wang, J. Zhao, and S.-Q. Cai, "Antiaging effect of Cordyceps sinensis extract," Phytotherapy Research, vol. 23, no. 1, pp. 116-122, 2009.

Traditional Chinese medicine is not yet a recognized health practice. The disorders mentioned are considered from a non-diagnostic point of view. Any treatments mentioned are intended as treatments to promote the rebalancing of the body and the general well-being of the person and should NOT be understood as therapy, cure, for which you should consult your doctor.