Ganoderma

Ganoderma lucidum

Immunostimulant, Cardiovascular, Antioxidant, Antiinflammatory, Antiallergic, Antiviral

ACTIVE: TRITERPENES, GANODERMIC ACID, POLYSACCHARIDES, LUCIDENIC ACID, NUCLEOSIDES, ERGOSTEROLS

TRADITIONAL CHINESE MEDICINE-ADAPTOGENESIS

Tonifies qi, nourishes the blood and calms the mind

Meridians: heart, spleen, stomach, liver, lung

Associated Elements: water, wood, fire

AN ICON OF TRADITIONAL CHINESE MEDICINE

The ancients thought that there were five indispensable qualities of life, Wood, Fire, Earth, Metal and Water, known as the five phases. Each of them possesses different characteristics, and all phenomena and things within the universe belong to one of these five phases.

The idea that has developed through the five-phase theory is that all phenomena and things in the universe are products of the movement and mutation of these five phases. It is also the philosophical theory of Traditional Chinese Medicine.

In this context, Ganoderma fits in as the buttress that inextricably links the two disciplines. Its fruiting body as well as mycelium and spores, have always, been used in Traditional Chinese Medicine to treat liver, hypertension, blood sugar, asthma, insomnia, as an anti-inflammatory, antioxidant and immunomodulatory.

Modern science has sequenced well over sixteen thousand genes in Reishi, they constitute the intervention pool of our mushroom since by going to code for several cytochrome P450 enzymes they superintend the production of many secondary active metabolites involved in maintaining our good health.

In today's day and age, Ganoderma is added to a little bit of everything, we firmly believe that the intake as an infusion offered by eikes remains the Olympic yardstick of comparison for any type of product.

BIBLIOGRAPHY

Wasson, R.G.. Soma: Divine Mushroom of Immortality; Harcourt Brace Jovanovich, Inc: Los Angeles, CA, USA, 1968; 80-92.

Smith, J.; Rowan, N.; Sullivan, R. Medicinal Mushrooms. Their Therapeutic Properties and Current Medical Usage with Special Emphasis on Cancer Treatment; Special Report Commissioned by Cancer Research UK; The University

of Strathclyde in Glasgow, 2002; 256.

 Liu, G.T. Recent advances in research of pharmacology and clinical applications of Ganoderma P. Karst. species (Aphyllophoromycetideae) in China. Int. J. Med. Mushrooms 1999, 1 (1), 63-68.

 Zhou, Sh.; Gao, Y. The immunomodulating effects of Ganoderma lucidum (Curt.: Fr.) P. Karst. (Ling Zhi, reishi mushroom) (Aphyllophoromycetideae). Int. J. Med. Mushrooms 2002, 4 (1), 1-11.

Jiang J, Grieb B, Thyagarajan A, Sliva D. Ganoderic acids suppress growth and inva- sive behavior of breast cancer cells by modulating AP-1 and NF-κB signaling. Inter- national Journal of Molecular Medicine 2008;21(5) 577-584.

Chen N-H, Liu J-W, Zhong J-J. Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression. Pharmacological Reports 2010;62(1) 150-163

] Jiang J, Grieb B, Thyagarajan A, Sliva D. Ganoderic acids suppress growth and inva- sive behavior of breast cancer cells by modulating AP-1 and NF-κB signaling. Inter- national Journal of Molecular Medicine 2008;21(5) 577-584.

Hsu C-L, Yu Y-S, Yen G-C. Lucidenic acid B induces apoptosis in human leukemia cells via a mitochondria-mediated pathway. Journal of Agricultural Chemistry 2008;56(11) 3973-3980.

Capasso L. 5300 years ago, the Ice Man used natural laxatives and antibiotics. The Lancet 1998;352(9143) 1864

Gao, Y., Tang, W., Dai, X., Gao, H., Chen, G., Ye, J., Chan, E., Koh, H.L., Li, X., & Zhou, S. (2005). Effects of water-soluble Ganoderma lucidum polysaccharides on the immune functions of patients with advanced lung cancer. Journal of Medicinal Food, Vol.8, No.2, (Summer 2005), pp. 159-168, ISSN 1096-620X

Gao, Y. H., Dai, X. H., Chen, G. L., Ye, J. X., & Zhou, S. F. (2003b). A randomized, placebocontrolled, multicenter study of Ganoderma lucidum (W.Curt.: Fr.) Lloyd (Aphyllophoromycetideae) polysaccharides (Ganoploy (R)) in patients with advanced lung cancer. International Journal of Medicinal Mushrooms, Vol.5, No.4, (December 2003), pp. 369-381, ISSN 1521-9437

Langevin, H.M., Badger, G.J., Povolny, B.K., Davis, R.T., Johnston, A.C., Sherman, K.J., Kahn, J.R., & Kaptchuk, T.J. (2004). Yin scores and yang scores: A new method for quantitative diagnostic evaluation in traditional Chinese medicine research. Journal of Alternative and Complementary Medicine, Vol.10, No.2, (April 2004), pp. 389-395, ISSN 1075-5535

Menendez-Arias, L. Targeting HIV: antiretroviral therapy and development of drug resistance. Trends Pharmacol. Sci. 2002, 23, 381-388.

 Vermani, K.; Garg, S. Herbal medicines for sexually transmitted diseases and AIDS. J. Ethnopharmacol. 2002, 80, 49-66.

 Eo, S.K.; Kim, Y.S.; Lee, C.K.; Han, S.S. Antiherpetic activities of various protein bound polysaccharides isolated from Ganoderma lucidum. J. Ethnopharmacol. 1999, 68, 175-181

 Schoch, C.L., Seifert, K.A., Huhndorf, S., Robert, V., Spouge, J.L., André Levesque, C., Chen, W., and Fungal Barcoding Consortium. 2012. "Nuclear ribosomal internal transcribed spacer (ITS) region as a universal DNA barcode marker for Fungi." Proc Natl Acad Sci. 109(16): 6241-6246.